Dr. Tanya Warwick is currently involved in several clinical trials focusing on both acute treatment of ischemic stroke and stroke prevention.  The following is a summary of trials currently enrolling at Community Regional Medical Centers.


“The Insulin Resistance Intervention after Stroke (IRIS) trial is a randomized clinical trial that will test the effectiveness of a new approach to preventing stroke and heart attack among patients with a recent ischemic stroke or TIA.  The new approach targets insulin resistance, a newly-recognized cause of atherosclerosis.  Atherosclerosis is the underlying disease that clogs vessels in strokes and heart attacks.  Insulin resistance affects nearly half of all patients with stroke and TIA.  Participating stroke patients will be assigned to receive pioglitazone, a medication which reduces insulin resistance, or placebo.”


SPS3 is a study for people who have experienced a small subcortical stroke also known as a lacunar stroke.  The main goal of this study is to learn more about preventing another stroke from happening to people who have already had a subcortical stroke.  We also want to learn how to prevent problems with thinking and memory decline that may happen after a stroke.  This study is testing if taking both aspirin and clopidogrel will be more effective in preventing another stroke than just aspirin alone.  As well, this study is seeking information about the best level of blood pressure control after a stroke.