Internal Medicine/Pulmonary and Critical Care Medicine


J. Joseph Vempilly, MBBS, MD, MRCP (UK), FCCP

Professor of Medicine, UCSF

Director, Pulmonary Function Lab, CRMC
Director , Respiratory Care, CRMC









    Medical School: St. Johns Medical College, Bangalore, India
    Residency: St. Johns Medical College, Bangalore, India
  Postgraduate: Royal College of Physicians, London, UK
  Fellowship: Pulmonary/Critical Care, Medical University of South Carolina, Charleston
    Board Certified:

Internal Medicine
Pulmonary Medicine

Critical Care

  Awards and Recognition:

Du-Pont Critical Care/ACCP Young Investigator Award 1990, American College of Chest Physicians Postdoctoral Research Fellowship Award. Division of Immunology, Medical University of South Carolina, Charleston, SC. 1994 Outstanding teacher award in Clinical Medicine 2005, Faculty of Medicine, UAE University, Al Ain Examiner, Royal College of Physicians: Examiner for PACES clinical examination, 2001-2005

Faculty research award, University of California, San Francisco, Fresno Medical Education 2011

  Grant Awards:

2008-2010,         Effects of Air Pollution, Viral Infection, and Genetics on Asthma in San Joaquin Valley:  Funded by Air Pollution Control District. J. Joseph J, A A. Hasson, T. Tyner, M . Rawat


2010-2011,A long-term, randomized, double-blind, parallel group study of fluticasone furoate/GW642444 inhalation powder once daily and fluticasone furoate inhalation powder once daily in subjects with asthma.


2012, A randomized, double blind, placebo controlled, parellel group study to assess the efficacy, safety and tolerability of SAR231893/REGN6668 administered subcutaneously once weekly for 1 weeks in patients with moderate to severe eosinophilic asthma who are partially controlled with inhaled corticosteroids.

    Consultant to Editorial Board: Annals of Internal Medicine from 1992 - 1995 Emirates Medical Journal from 1999

Chest from 2002

International Journal of Infectious Disease from 2003 Archives of Medical Science from 2004 Examiner, Royal College of Physicians:    Examiner for PACES clinical examination, 2001-2005
    Grant Awards:
  1. The role of transforming growth factor-B, decorin and 1 25 dihydroxy vitamin in animal model of granulomatous lung disease induced by Mycobacterium butyricum. 1995-1997, American Lung Association.
  2. The role of interleukins and transforming growth factor in the pathogenesis of asthma.  Hamadan Research Grant Award, Dubai, UAE from 2000 December
  3. The effect of TGF beta on in vitro production of TH2 cytokines and IgE by PBMC. Hamadan Research Grant Award, Dubai, UAE from 2002 December
  4. Comparison of Th-1 and Th-2 intracellular cytokine profiles between atopic and non-atopic asthmatics and their [clinical and biological]responses to a leukotriene receptor antagonist or corticosteroid therapy . Interdisciplinary grant, UAEU University, 2003-2005
  5. Air Pollution, Viral Infection, and Asthma Exacerbation:  Application of multiplex Immunoproteomics to Detect Biomarkers in Inflammation and Infection, a Collaborative Research Pilot Project, Fresno Air Board
  1. My current research is focused to assess the lung volume abnormalities and its correlation to various symptoms of asthma and volume reversibility in phenotypes of asthma.

    1. Abnormal residual volume and RV/TLC measured by body plethsmography may serve as a better clinical tool than spirometic indices in diagnosing obstruction and grading severity in asthma. Principal Investigator: Jose Joseph Vempilly MD,: Anupama Tiwari, Ali Rashidian, B. Abijie, Vipul Jain . Lung Volume Assessment in Astha. 2012 to 2015, Funded by CCFMG
    2. A Prospective Observational Pilot Study of Chronic Bronchiectasis Patients Assessing The Correlation of Lung Clearance Index Measured by Nitrogen Washout and Forced Expiratory Volume in 1st Second with Functional Capacity Using Six-Minute Walk Test.  PI: David Lee, MD, Co investigators: M. Iyad Saadi, MD. Jose Joseph Vempilly. Funded by CCFMG. 2015

1. Channabasaviah A, Joseph J. Thoracic endometriosis: Revisiting the Association Between Clinical Presentation and Thoracic Pathology Based on Thoracoscopic Findings in 110 Patients. MedicineVolume 89, Number 3, May 2010

2. Chitra Kandaswamy, M.D, M.P.H, Garrett Bird, M.D., C.M, Narinder Gill, M.D., Edward Math, M.D, Jose Joseph Vempilly, M.D. Severe Tracheomalacia in ICU: Identification of diagnostic Criteria and risk factor analysis from a case control study. RESPIRATORY CARE FEBRUARY 2013 VOL 58 NO 2.

3.  Lung Volume Abnormalities And Its Correlation To Spirometric and demographic variables In Adult Asthma V.Jain, Belaynaih Abejie, M Bashir, T.Tyner, Vempilly Joseph J,

4. Vempilly Jose, Belayneh Abejie, Vivian Diep, Melissa Gushiken, Mamta Rawat, and Tim R. Tyner. The synergetic effect of ambient PM2.5 exposure and rhinovirus infection in airway dysfunction in asthma: A pilot observational study from the central valley of california Experimental Lung           Research, Early Online, 1–7, 2013

5.  Methylene Blue Is Effective to Reverse Refractory Hemodynamic Instability due to Dimethoate Poisoning. Nick Youssefi; Rais Vohra; Jose Joseph-Vempilly; Zacharia Reagle. Asia Pacific Jr Med Toxicol. Volume 4, Issue 3, Summer 2015, Page 123-126.

6.  Ghahremani-Ghajar M, Harada S, Tabassomi M, Vempilly JJ.  An Unusual Case of Resistant Hepatic Hydrothorax Treated with Octreotide Infusion.  McGill Journal of Medicine in press 2013.

7. Vempilly J, Abejie B, Diep V, Gushiken M, Rawat M, Tyner TR. The synergetic effect of ambient PM2.5 exposure and rhinovirus infection in airway dysfunction in asthma: A pilot observational study from the central valley of california. Exp Lung Res. 2013 Dec; 39(10):434-40. PMID: 24245976


8. Nick YoussefiRais VohraJose Joseph-VempillyZacharia Reagle. Methylene Blue Is Effective to Reverse Refractory Hemodynamic Instability due to Dimethoate Poisoning. Articles in Press, Accepted Manuscript, Available Online from 25 September 2015


9. Office spirometry correlates with laboratory spirometry in patients with symptomatic asthma and COPD.
Bambra G1, Jalota L1, Kapoor C2, Mills PK2, Vempilly JJ1, Jain VV1. Clin Respir J. 2015



Monographs and
Book Chapters:

  1. Joseph J, Sahn SA. Thoracic Endometriosis. Up Todate 2012-15
  2. J Joseph, Sahn SA. Pleural effusions in AIDS. Up Todate 2012-15

J Joseph Vempilly: Approach to pleural effusion. 2015 in print: Text book of pulmonary and critical care; Jaypee Brothers Medical Publishers, Edited by Jindal S.K