Internal Medicine/Cardiology


John A. Ambrose, MD, FACC
Professor of Medicine, UCSF
Chief of Cardiology, UCSF
Program Director, Cardiology Fellowship

Medical School:

New York Medical College, New York


Mount Sinai Hospital, New York


Mount Sinai Hospital, New York

Board Certified:

National Board of Medical Examiners
American Board of Internal Medicine
American Board of Internal Medicine, Cardiology

Awards and Recognition:

  1. Best Doctors in America

  2. Simon Dack Award for Best Teacher in Cardiology              

  3. New York Medical College Alumni Assoc. Gold Medal of Honor

  4. NRCC National Leadership Award

  5. Physician’s Advisory Board (NRCC) Honorary Co-Chairman

  6. St. Vincent’s Hospital Honored Teacher Award 



Publications (last 5 years):  
  1. Puttappa R, Raia F, Bhat S, Braff R, Mandadi V, BaruaRS, DeVoe MC, Boal BH, Ambrose JA. Peripheral left bundle branch block in left ventricular dysfunction. Am J Cardiol 2003;91:354-6

  2. Zairis, MN, Ambrose JA, Papadaki OA, Manousakis SJ, Stefanidis AS, DeVoe MC, Handanis SM, Olympios CD, Foussas SG. C-reactive protein and ST-segment monitoring by continuous 12-lead electrocardiogram in patients with primary unstable angina pectoris. Am J Cardiol 2003;91:600-3.

  3. Barua RS, Ambrose JA, Saha DC, Svrivastava S, DeVoe MC, Eales-Reynolds LJ.  Reactive oxygen species are involved in smoking-induced dysfunction of nitric oxide biosynthesis and up-regulation of endothelial nitric oxide synthase: an in vitro demonstration in human coronary artery endothelial cells.  Circulation 2003;107:2342-7.

  4. Ambrose JA, Gould RB, Kurian DC,DeVoe MC, Pearlstein NB, Coppola JT, Siegal FP. Frequency of and outcome of acute coronary syndromes in patients with human immunodeficiency virus infection. Am J Cardiol 2003;92:301-3.

  5. Tousoulis D, Davies G, Stefanadis C, Toutouzas P, Ambrose JA. Inflammatory and thrombotic mechanisms in coronary atherosclerosis. Heart. 2003 Sep;89(9):993-7

  6. Rodríguez AE, Rodriguez Alemparte  M, Vigo CF, Curotto  V, Fernández Pereira C, Llauradó C,  Martínez J, Virmani R, Ambrose JA. Oral Rapamycin to Prevent Restenosis in Patients Undergoing Coronary Stent Therapy:  Argentina Single Center Study (ORAR Trial). J Inv Cardiol 2003.

  7. Heiba SI, Ambrose JA, Value of Low Dose Dobutamine Addition to Routine Dual Isotope Gated Spect Myocardial Imaging in Ptients with Healed Myocardial Infarcts or Abnormal Wall Thickening by Echocardiogram.  Am J Cardiol 2004;93:210-213
  8. Meireles GCX,Lemos PA,Ambrose JA et al.Luminal recovery from six to twelve months after implantation of  “thicker strut” coronary stents. Am J Cardiol 2004;93:210-213.

  9. Zairis MN, Ambrose JA, Lyras AG, Thoma MA, Psarogianni PK, Psaltiras GP,  Kardoulas AD, Bibis GP, Pissimissis EG, Batika PC, DeVoe MC, Prekates AA, Foussas SGC-Reactive Protein, Moderate Alcohol Consumption and Long Term Prognosis After Successful Coronary Stenting Four Years Results From the GENERATION Study. (Global Evaluation of New Events and Restenosis After stenT implantatION). Heart Jnl 2003.

  10. Mandadi V, DeVoe MC, Ambrose JA, Prakash AM, Varshneya N, Gould RB, Nguyen TH, Geagea J-P M Radojevic JA, Sehhat K, Barua RS. Predictors of troponin elevation after percutaneous coronary intervention. Am J Cardiol. 2004 ;93:747-750.

  11. Ambrose JA and Barua RS.  The pathophysiology of cigarette smoking and cardiovascular disease: An update. J Am Coll Cardiol 2004;43:1731-1737.

  12. D`Agate DJ, Patel S, Coppola JT, Ambrose JA. The evolving role of glycoprotein 2b/3a receptor blockade during percutaneous coronary intervention of saphenous vein bypass grafts. J of Inv Cardiol 2004;16:500-05.

  13. Ambrose JA and D’Agate DJ.  A new classification of potential therapies for plaque stabilization.  Am J Cardiol 2005;95: 379-382.

  14. Zairis MN, Ambrose JA, Amartzidou O etal. Preprocedural plasma CRP levels, post procedural CK-MB release and long-term prognosis after successful coronary stenting ( 4 year results of the GENERATION study ) Am J Cardiol 2005;95:386-90.

  15. Ambrose JA, D`Agate DJ. Plaque rupture and intracoronary thrombus in non-culprit vessels: an eyewitness account. J Am Coll Cardiol 2005;45:659-60.

  16. Liuzzo JP, Shin YT, Lucarello R, Klapholz M, Lang SJ, Braff R, Coppola JT, Ambrose JA. Triple valve repair for rheumatic heart disease .J of Card Surg 2005;20:358-63.

  17. Liuzzo JP, Ambrose JA, Coppola JT.  Sirolimus-and taxol-eluting stents differ towards intimal hyperplasia and re-endothelialization. J Invasive Cardiol 2005;17:497-502.

  18. Hannan EL. Wu C, Walford G. King SB 3rd, Holmes DR Jr, Ambrose JA, Sharma S. Katz S, Clark LT, Jones RH.  Volume-outcome relationships for percutaneous coronary interventions in the stent era. Circulation 2005;112:1171-9.

  19. Foussas SG, Zairis MN, Lyras AG, Patsourakos NG, Tsirimpis VG, Katsaros K, Beldekos DJ, Handanis SM, Mytas DZ, Karidis KS, Tselioti PG, Prekates AA, Ambrose JA.  Early prognostic usefulness of C-reactive protein added to the Thrombolysis In Myocardial Infarction risk score in acute coronary syndromes.  Am J Cardiol 2005;96:533-7.

  20. Liuzzo JP, Ambrose JA and Diggs P. Proton pump inhibitors for patients with coronary artery disease associated with reduced chest pain, emergency department visits and hospitalizations. Clin Cardiol 2005;28:369-374.

  21. Wu C, Hannan EL, Walford G, Ambrose JA, Holmes DR, King III SB, Clark LT, Katz S, Sharma S and Jones RH. A risk score to predict in-hospital mortality for percutaneous coronary interventions. J Am J Cardiol 2006; 47:654-60.

  22. Staniloae C, Mandadi V, Kurian D, Bernaski E, El-Kally Z, Morlote M, Pinassi E, Ambrose JA. Pioglitazone improves endothelial function in non-diabetic patients with coronary artery disease. Cardiology 2006;108:164-169.

  23. Pimental WC, Martinez EE, Ambrose JA et al. Human myocardium preconditioning during successful balloon inflations: irrelevant influence of both collateral recruitment and clinical pre-intervention interference. Euro Interv.2006;2:345-350.

  24. Hannan EL, Raczm, Holmes DR, King SB III, Walford G, Ambrose JA, Sharma S, Katz s, Clark LT Jones RH. Impact of completeness of PCI revascularization on long-term outcomes in the stent era. Circulation 2006;113:2406.

  25. Zalc S, Ambrose JA, Lemos PA et al. Myocardial perfusion scintigraphy to predict outcomes after coronary stenting. Euro Intervent 2006.

  26. Srikanth S, Barua R, Ambrose JA. Methamphetamine-Associated Acute Left Ventricular Dysfunction: A Variant of Stress-Induced Cardiomyopathy. Cardiology. 2007 Aug 30;109(3):188-192.

  27. Ambrose JA. In search of the “vulnerable plaque” Can it be localized and will focal regional therapy ever be an option for cardiac prevention? J Am Col Cardiol 2008;51:1539-42.

  28. Friedwald VE, Ambrose JA, Willerson JT, et al. The Editor’s Round table – Vulnerable Plaque. American Journal of Cardiology (in press).

  29. Javed U, Aftab W, Ambrose JA, et al. Troponin elevation and the universal definition of acute myocardial infarction. Journal of American College of Cardiology (submitted for publication).

  30. Barua R, Sy F, Ambrose JA, et al. The effects of cigarette smoking on in-vitro thrombolysis and fibrin architecture. Circulation (submitted for publication).