Internal Medicine/Neurology

Jeffrey Rosenfeld, MD
, PhD
    Professor of Clinical Neurology (pending)
  Medical School: University of Maryland
  Residency: Hospital of the University of Pennsylvania
  Masters:

University of Connecticut
Neuromorphology/Neuroanatomy

  Doctorate:

University of Connecticut
Neuromorphology/Neuroanatomy

 

Post-Doctoral Research Fellowship:

Johns Hopkins University School of Medicine
  Board Certified: Neurology
  Awards and Recognition:
    • American Neurologic Association ( ANA, elected membership)
    • American Academy of Neurology – Fellow (FAAN)
    • American Homecare and Hospice Physician of the Year 2006
    • Chairman, ALS Association Clinical Grant Committee.
    • MDA Annual Spirit Award 2007
    • America’s Best Doctors  2004-2008
    • Muscular Dystrophy Association Outstanding Clinic Award
    • Zeritsky Research Award, Department of Neurology, University of Pennsylvania
    • Maryland State Senatorial Scholarship
    • Combined Accelerated Program in Psychiatry (CAPP)
    • University of Maryland School of Medicine Competition, 1st, 2nd, 4th prize.
    • University of Maryland School of Medicine
    • Honors in Neurology
    • Honors in Pathology Research
    • Honors in Neuroscience
    • International Motor Neuron Disease Association – program committee
  Publications: (last 5 years)  
   
  1. Jackson, CE, Rosenfeld, J., Gronseth, G., Barohn, RJ, Dubinsky, R., Simpson, CB, McVey, A., King, RM, Hurbelin, L., and the Muscle Study Group.  A Randomized, Double-Blind Study of Botulinum Toxon type B for Sialorrhea in Patients with ALS.  In press, Muscle Nerve 2008.
  2. DiBernardo, A., Cudkowicz, J., Groveneveld, G., van den Berg, L., Zhang, H., Schoenfield, D., Rosenfeld, J., Combined analysis of creatine trials in patients with Amyotrophic Lateral Sclerosis.  Submitted 2008.
  3. Rosenfeld, J., King, R.M., Jackson, C.E.,Bedlack, R.S., Barohn R., Dick, A., Phillips, L., Chapin, J., Gelinas, D., Lou, J-S  Creatine monohydrate in Amyotrophic Lateral Sclerosis: Effects on strength, fatigue, respiratory status and ALSFRS.  In press Amyotrophic Lateral Sclerosis 9(5) 266-272 2008.
  4. Miller, R.G, Jackson, C.E., Kasarskis, E.J., England, J., Forshew, D., Johnston, W.,  Kalra, S., Katz, J.S., Mitsumoto, H., Rosenfeld, J., Shoesmith, C., Strong, M.J., Woolley-Levine, S.and the ALS Practice Parameter Task Force*. Practice Parameter Update: The Care of the Patient with Amyotrophic Lateral Sclerosis (An Evidence-Based Review): Report of the Quality Standards Subcommittee of the American Academy of Neurology.  In press Neurology  2008.
  5. Rosenfeld J. Ellis A. Nutrition and dietary supplements in motor neuron disease. Physical Medicine & Rehabilitation Clinics of North America. 19(3):573-89, x, 2008 Aug.
  6. Hemendinger RA. Armstrong EJ 3rd. Persinski R. Todd J. Mougeot JL. Volvovitz F. Rosenfeld J.  Huperzine A provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death. Neurotoxicity Research. 13(1):49-61, 2008 Jan.
  7. Dunckley, T., Craig, D.W., Huentelman, M.J., Pearson J., Szelinger, S.  Joshipura, K., Halperin, R., Stamper, C.,  Letizia, D., Hesterlee, S.E., Pestronk, A., Levine, T., Bertorini, T., Graves, M.C., Mozaffar, T., Jackson, C.E., Bosch, P., Barohn, R., Lomen-Hoerth C., Rosenfeld, J., O’Connor, T., Zhang, K., Crook, R., Hutton, M., Ryberg H., Mitsumoto, H., Bowser, R., Miller, R.G., Appel, S.H.,  Stephan, D.A., . Whole-genome analysis of sporadic amyotrophic lateral sclerosis. New England Journal Medicine 357(8) 775-88 2007.
  8. Keramaris-Vrantsis, E.,Lu, P.J., Doran, T., Zillmer, A., Ashar, J.,  Esapa, C.T., Benson M.A., Blake, D.J., Rosenfeld, J., Lu, Q.L.  Fukutin-related protein localizes to the Golgi apparatus and mutations lead to mis-localization in muscle in vivo.  Muscle Nerve.  36(4) 455-65 2007.
  9. Alexander V Panov, A.V., Dikalov, S., Shalbuyeva, N., Hemendinger, R., Greenamyre, J.T., Rosenfeld, J. Species and Tissue Specific Relationships Between Mitochondrial Permeability Transition and Generation of ROS in brain and Liver Mitochondria of Rats and mice.  American Journal of Physiology: Cell Physiology 292 C708-C718 2007.
  10. Rosenfeld, J., Swash, M.  What’s in a name?  Lumping or splitting ALS, PLS, PMA and the other motor neuron diseases.  Neurology 66 1-2 2006.
  11. Alter J. Lou F. Rabinowitz A. Yin H. Rosenfeld J. Wilton SD. Partridge TA. Lu QL. Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology. [Journal Article] Nature Medicine. 12(2):175-7, 2006 Feb.
  12. Hemendinger, R.,  Wang J. , Malik, S. Persinski, R., Copeland, J., Emerich, D.,  Gores, P., Halberstadt C. and Rosenfeld, J.. Sertoli cells improve survival of motor neurons in SOD1 transgenic mice, a model of amyotrophic lateral sclerosis. Exp. Neurology, 196:235-243  2005.
  13. Rosenfeld, J.  Drug Cocktails. Amyotrophic Lateral Sclerosis & Other Motor Neuron Disorders Suppl 1 1-3.  2004.
  14. Rosenfeld, J   Multi-drug ‘Cocktail’ Therapy in Amyotrophic Lateral Sclerosis:  The Case For a Multi-drug Approach  Muscle Nerve 2004.
  15. Cameron, A., Rosenfeld, J.  The Role of Creatine in the Management of Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disorders   CNS Drugs 18(13) 1-14 2004.
  16. Strong M, Rosenfeld J. Amyotrophic lateral sclerosis: a review of current concepts.  Amyotrophic Lateral Sclerosis & Other Motor Neuron Disorders. 2003;4:136-143.
  17. Cudkowicz ME, Shefner JM, Schoenfeld DA et al. A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis.[see comment]. Neurology. 2003;61:456-464.
  18. Mitsumoto H, Davidson M, Moore DH, Gad N, Brandis M, Ringel SP, Rosenfeld J, Shefner JM, Strong MJ, Sufit R, Anderson FA. Percutaneous endoscopic gastrostomy (PEG) in patients with ALS and bulbar dysfunction. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 2003; 4:177-185.
  19. Strong, M, Rosenfeld, J.. Amyotrophic Lateral Sclerosis. ALS and other Motor Neuron Disorders 2003 4, 1-8.

 


 

 

 


 

 

 


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