Internal Medicine/Pulmonary and Critical Care, Sleep Medicine



Wee Kiat (David) Lee, MD

Assistant Clinical Professor of Medicine







  Medical School:

University of Calgary Faculty of Medicine, Alberta, Canada

  Residency: University of Massachusetts
  Fellowship: Pulmonary/Critical Care, Rhode Island Hospital/Brown University
  Board Certified: Internal Medicine, Pulmonary, Critical Care Medicine, &  Sleep Medicine
  Awards and Recognition:

Joseph Albert Memorial Award for best research in the undergraduate medical school 2003 for the project "Epidemiology and Impact of interpersonal violence in Calgary, a project of the Calgary Trauma Research Group"

Top Ranked Intern, as voted by attendings (2003-2004)
Top Ranked Resident as voted by peers (2005)

Elected to Fellow of the American College of Chest Physicians, 2013

  Publications (since 2009):

Braman S, Lee D.  Primary care management of chronic obstructive pulmonary disease: an integrated goal-directed approach.  Current Opinion in Pulmonary Medicine 2010.  16(2):83-88.  PMID:  20010105

Aliotta JM, Pereira M, Johnson KW, de Paz N, Dooner MS, Puente N, Ayala C, Brilliant K, Berz D, Lee D, Ramratnam B, McMillan PN, Hixson DC, Josic D, Quesenberry PJ.  Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription.  Exp Hematol. 2010 March; 38(3): 233–245.  PMID:  20079801

Aliotta JM, Lee D, Puente N, Faradyan S, Sears EH, Amaral A, Goldberg L, Dooner MS, Pereira M, Quesenberry PJ.  Progenitor/stem cell fate determination: interactive dynamics of cell cycle and microvesicles.  Stem Cells Dev. 2012 Jul 1;21(10):1627-38.  PMID:  22214238

Stanchina ML, Lee D et al. Impact of CPAP use and age on mortality in patients with combined COPD and obstructive sleep apnea: the overlap syndrome. J Clin Sleep Med 2013 Aug 15;9(8):767-72.  PMCID: PMC3716667

Andrews S, Lee D. Mounier-Kuhn syndrome presenting as cough. Am J Resp Crit Care Med 2014; (189): 1141.  PMID:  24787068


Books and Chapters

The management of stable asthma.  Lee D, Braman S.  Textbook of Pulmonary and Critical Care Medicine by Jaypee Brothers Medical Publishers Pvt.Ltd.2010



Conference Abstracts


Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription.  American Thoracic Society Meeting 2010 March; 38(3): 233–245.

Impact of CPAP compliance on mortality in patients with combined COPD and OSA.  American Thoracic Society Annual Meeting 2011 Denver, CO.

Clinical Use Of Loop Gain Measures To Determine CPAP Efficacy In Patients With Complex Sleep Apnea. Am J Respir Crit Med 187; 2013: A3760





A Prospective Observational Study Of Chronic Bronchiectasis Patients Assessing The Correlation Of Lung Clearance Index Measured By Nitrogen Washout And Forced Expiratory Volume In 1st Second With Functional Capacity Using Six-Minute Walk Testing


Principal investigator for a multi-center controlled study titled "Randomized Trial of Ticagrelor for Severe Community Acquired Pneumonia" 


Principal investigator for a multi-center SSAIL study in the ICU. Study: Treatment of Septic Shock by inhibiting Auto-digestion and Preserving gut integrity with Enteric LB1148 (SSAIL study)


Sub-investigator for APEX study: Acute Medically ill VTE prevention with extended duration Betrixaban Study (APEX)