Internal Medicine


Vipul V. Jain, MD, MS

Associate Professor of Medicine, UCSF
Director, Chronic Lung Disease Program, UCSF Fresno
Director, Smoking Cessation Program, UCSF Fresno










Medical School:

T.N. Medical College, Bombay, India
  Residency: UCSF Fresno
  Post Graduate: University of Iowa
  Fellowship: Pulmonary/Critical Care, University of California San Diego
  Board Certified: Internal Medicine
Pulmonary Medicine
Critical Care Medicine
  Awards and Recognition UCSF Fresno, Internal Medicine, Intern of the Year
UCSF Fresno, Internal Medicine, Research Award
Member, Editorial Board. Journal of Asthma   
Reviewer, Medical Science Monitor 
Reviewer, Clinical and Experimental Dermatology
Election to Index Copernicus Panel of Scientists (2007)


  Publications (since 2004):

Kline JN, Kitagaki K, Businga TR, Jain VV. Treatment of Established Asthma in a Murine Model Using CpG Oligodeoxynucleotide. Am J Physiol 2002 Jul;283(1):L170-9

Hussain I, Jain VV, Kunihiko K, Businga TR, O'Shaughnessy PT, Kline JN.Modulation of Murine Allergic Rhinosinusitis by CpG Oligodeoxynucleotides. Laryngoscope 2002 Oct;112(10):1819-26

Kitagaki K, Jain VV, Businga TR, Kline JN. Immunomodulatory effects of CpG oligonucleotides on established Th2 responses. Clin Diagn Lab Immunol 2002 Nov; 9(6):1260-69

Jain VV,Kitagaki K, Businga TR, Hussain I, George CL, O'Shaughnessy P, Kline JN. CpG-Oligodeoxynucleotides Inhibit Airway Remodeling in a Murine Model of Chronic Asthma. J Allergy Clin Immunol 2002;110:867-72

Jain VV,Businga TR, Kitagaki K, Hussain I, O'Shaughnessy P, Kline JN. Mucosal Immunotherapy with CpG Oligodeoxynucleotides Reverses a Murine Model of Chronic Asthma Induced by Repeated Antigen Exposure. Am J Physiol 2003 Nov:285(5):L1137-46

Jain VV,Kitagaki K,Kline JN. CpG DNA and Immunotherapy of Allergic Airway Diseases. Clin Exp Allergy 2003 Oct:33(10):1330-35

Hussain I, Jain VV, O'Shaughnessy P, Businga TR, Kline JN.Effect of Nitrogen Dioxide exposure on Allergic Asthma in a Murine Model. Chest 2004 Jul;126(1):198-204

Jain VV, Kline JN. CpG DNA: Immunomodulation and Remodeling of the Asthmatic Airway. Expert Op Biol Ther 2004: 4(9); 1533-1540

Jen KY, Jain VV, Makani S, Finn PW. Immunomodulation of allergic responses by targeting costimulatory molecules. Curr Opin Allergy Clin Immunol 2006 Dec; 6(6): 489-94

Lu X, Jain VV, Finn PW, Perkins DL. Hubs in gene network exhibit low changes in expression in allergic response in experimental asthma. Mol Syst Biol 2007 April, 3:98

Jain VV, Perkins DL, Finn PW. Applying Systems Biology Approaches to Costimulation in Allergic Inflammation. Pharmacol Ther 2008 Mar, 177, Issue 3 385-392

Jain VV, Abejie B, Bashir MH, Tyner T, Vempilly J. Lung Volume Abnormalities and its correlation to spirometric and demographic variables in adult asthma. J Asthma. 2013 Aug;50(6):600-5

Jain VV, Allison R, Beck S, McCurley J, Jain R, Mills PK, Van Gundy KP, Peterson MW. Impact of an Integrated Disease Management Program in reducing Exacerbations in patients with Severe Asthma and COPD. Respiratory Medicine (in press, Aug 2014)




ABSTRACTS (selected since 2002)


Jain VV, Businga TR, Kitagaki K, Kline JN. CpG ODN inhibit airway remodeling by repeated allergen exposure. Am J Respir Crit Care Med 165 (8):592 2002

Jain VV, Businga TR, Kitagaki K, Kline JN. Regulatory role for C3 in allergic lung inflammation. Am J Respir Crit Care Med 165 (8):592 2002


Jain VV, Rodriguez AIII, Elliott S, Peterson MW. Adherence to asthma guidelines for spirometry testing: role of physician understanding in a training program. Proc. Am. Thor. Soc 2:A911: 2005

Jain VV, Bigby TD. Neurologic sequelae of subclavian vein catheterization. Crit Care Med 34(12) Dec 2006

Jain VV, Xin Lu, Finn PW, Perkins DL. Gene Ontology Analysis Reveals A Core Set Of Biological Processes Orchestrating Allergic Asthmatic Responses Am J Respir Crit Care Med 175:A389 Apr 2007

Jain VV, Xin Lu, Finn PW, Perkins DL. Systems Biology Analysis Identifies Critical Signal Transduction Pathways In Allergic Asthmatic Responses Am J Respir Crit Care Med 175:A388 Apr 2007

Jain VV, Dimsdale JE, Ancoli-Israel S, Bardwell W, Palinkas L, Loredo JS. Snoring is an Independent Risk Factor for Asthma in Hispanics. Sleep June 2008

Avik E, Jain VV. Characteristics of Hemothoraces from Rib Exostosis: Case report and Review of 21 cases. Am J Respir Crit Care Med 185;2012:A2983

Allison R, Andrews S, Jain R, Van Gundy KP, Peterson MW, Jain VV. Overdiagnosis Of Severe Asthma And COPD In The Setting Of Underutilization Of Spirometry. Am J Respir Crit Care Med 189:A2972; 2014

Avik EL, Andrews SM, Deguzman, J, Jain VV. Recurrent Lymphocytic Pleural And Pericardial Effusions Associated With Familial Late-Onset Lymphedema. Am J Respir Crit Care Med 189; A2911; 2014

Kapoor C, Bambra G, Mills P, Vempilly J, Jain VV. Evidence Of Correlation Between Office Spirometry And Laboratory Spirometry In Patients With Asthma And COPD. Am J Respir Crit Care Med 189;A2975;  2014


Jain VV, Allison R, Beck S, Van Gundy KP, Peterson, MW. Impact Of A University Based Comprehensive Chronic Lung Disease Program On Hospital Utilization In Patients With Severe Asthma And COPD. Am J Respir Crit Care Med 189;A1911,  2014