Vipul V. Jain, MD, MS

Assistant Clinical Professor

Medical School:

T.N. Medical College, Bombay, India

University of California San Diego

Internal Medicine
Pulmonary Medicine

UCSF Fresno, Internal Medicine, Intern of the Year
UCSF Fresno, Internal Medicine, Research Award

1. Kline JN, Krieg AM, Waldschmidt TJ, Ballas ZK, Jain V, Businga TR. CpG oligodeoxynucleotides do not require TH1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma. J Allergy Clin Immunol 1999:104(6): 1258-64

2. Kline JN, Kitagaki K, Businga TR, Jain VV. Treatment of Established Asthma in a Murine Model Using CpG Oligodeoxynucleotide. Am J Physiol 2002 Jul;283(1):L170-9

3. Hussain I, Jain VV, Kunihiko K, Businga TR, O'Shaughnessy PT, Kline JN. Modulation of Murine Allergic Rhinosinusitis by CpG Oligodeoxynucleotides. Laryngoscope 2002 Oct;112(10):1819-26

4. Kitagaki K, Jain VV, Businga TR, Kline JN. Immunomodulatory effects of CpG oligonucleotides on established Th2 responses. Clin Diagn Lab Immunol 2002 Nov; 9(6):1260-69

5. Jain VV, Kitagaki K, Businga TR, Hussain I, George CL, O'Shaughnessy P, Kline JN. CpG-Oligodeoxynucleotides Inhibit Airway Remodeling in a Murine Model of Chronic Asthma. J Allergy Clin Immunol 2002;110:867-72  

6. Jain VV, Businga TR, Kitagaki K, Hussain I, O'Shaughnessy P, Kline JN. Mucosal Immunotherapy with CpG Oligodeoxynucleotides Reverses a Murine Model of Chronic Asthma Induced by Repeated Antigen Exposure. Am J Physiol 2003 Nov:285(5):L1137-46

7. Jain VV, Kitagaki K, Kline JN. CpG DNA and Immunotherapy of Allergic Airway Diseases. Clin Exp Allergy 2003 Oct:33(10):1330-35

8. Hussain I, Jain VV, O'Shaughnessy P, Businga TR, Kline JN. Effect of Nitrogen Dioxide exposure on Allergic Asthma in a Murine Model. Chest 2004 Jul;126(1):198-204

9. Jain VV, Kline JN. CpG DNA: Immunomodulation and Remodeling of the Asthmatic Airway. Expert Op Biol Ther 2004: 4(9); 1533-1540

10. Jain VV, Evans T, Peterson MW. Reactivation Histoplasmosis After Treatment with Tumor Necrosis Factor α In A Patient From A Nonendemic Area. Respir Med 2006 Jul 100 (7): 1291-3

11. Jen KY, Jain VV, Makani S, Finn PW. Immunomodulation of allergic responses by targeting costimulatory molecules. Curr Opin Allergy Clin Immunol 2006 Dec; 6(6): 489-94

12. Lu X, Jain VV, Finn PW, Perkins DL. Hubs in gene network exhibit low changes in expression in allergic response in experimental asthma. Mol Syst Bio 2007 Apr; 3:98

13. Jain VV, Perkins DL, Finn PW. Applying Systems Biology Approaches to Costimulation in Allergic Airway Inflammation. Pharmacol Ther 2008 Mar, 117, Issue 3 385-392

14. Jain VV, Lu X, Finn PW, Perkins DL. Genetic Susceptibility to Asthma Differentiated by Quantitative Changes in Gene Expression. PLOS Comp Biol 2007 (Submitted)

Abstracts

1. Jain VV, Xin Lu, Finn PW, Perkins DL. Gene Ontology Analysis Reveals A Core Set Of Biological Processes Orchestrating Allergic Asthmatic Responses Am J Respir Crit Care Med  175:A389 Apr 2007
   
   
2. Jain VV, Xin Lu, Finn PW, Perkins DL. Systems Biology Analysis Identifies Critical Signal Transduction Pathways In Allergic Asthmatic Responses Am J Respir Crit Care Med  175:A388 Apr 2007
   
   
3. Jain VV, Bigby TD. Neurologic sequelae of subclavian vein catheterization. Crit Care Med 34(12) Dec 2006

4. Jain VV, Rodriguez AIII, Elliott S, Peterson MW. Adherence to asthma guidelines for spirometry testing: role of physician understanding in a training program. Proc. Am. Thor. Soc2:A911: 2005
   
   
5. Kitagaki K, Jain VV, Businga TR, Hussain I, Kline JN.  In Vivo Modulation of Antigen-Induced Airway Inflammation by Antigen Presenting Cells Pulsed with CpG-ODN and Antigen. Am J Respir Crit Care Med  A725: 2003
   
   
6. Kitagaki K, Jain VV, Businga TR, Hussain I, Kline JN.  Stimulation of CD19+ and CD11c+ Cells with CpG ODN Differently Modulate Antigen-Induced Th1 and Th2 Cytokine Production by CD4+ cells. Am J Respir Crit Care Med  A725: 2003
   
   
7. Jain VV, Businga TR, Kitagaki K, Kline JN. CpG ODN inhibit airway remodeling by repeated allergen exposure. Am J Respir Crit Care Med  165 (8):592 2002
   
   
8. Jain VV, Businga TR, Kitagaki K, Kline JN. Regulatory role for C3 in allergic lung inflammation. Am J Respir Crit Care Med  165 (8):592 2002
   
   
9. Kline JN, Jain VV, Kitagaki K, Businga TR, Hussain I. Allergen immunotherapy with CpG ODN reduces recall responses to a second allergen in a murine model of asthma. Am J Respir Crit Care Med  165 (8):592 2002
   
   
10. Kitagaki K, Jain VV, Businga TR, Kline JN. Modulation of antigen-specific TH2 response by antigen presenting cells pretreated with CPG ODN plus antigen. Am J Respir Crit Care Med 2002;165,A243
    
    
11. Chen CC, Zhengyi W, Jain VV, Nuno DW, Barresi R, Weiss RM, Kline JN, Lamping KG, Hill JA, Williamson R, Campbell KP. Functional studies of cav3.2 calcium channels using a gene-targeted strategy. Biophysical meeting. 2002.
    
    
12. Hussain I, Jain VV, O'Shaughnessy PT, Businga TR, Kline JN. Exposure to Nitrogen Dioxide Induces Tolerance to Airway Hyperresposiveness in A Murine Model of Asthma. J Allergy Clin Immunol (World Asthma Meeting) 2001.
    
    
13. Kitagaki K, Businga TR, Jain VV, Kline JN. CpG oligonucleotides can block Th2-type responses in the absence of IFN-gamma and IL-12. Am J Respir Crit Care Med 163(4): Mar 2001
    
    
14. Botta RS, Grant JA, Jain VV, Ballas ZK, Hussain I. Role Of Montelukast In Chronic Idiopathic Urticaria. J Allergy Clin Immunol (ACAAI Meeting) 2001
    
    
15. Jain VV, Kline JN, Businga TR. CpG Oligonucleotides provide effective adjuvant activity in a murine model of mucosal immunotherapy for asthma. Am J Respir Crit Care Med 161(3):A592 March 2000
    
    
16. Kline JN, Businga TR, Jain VV, Hussain I. Oral administration of CpG Oligonucleotides provide protection against inflammation in asthma. Am J Respir Crit Care Med 161(3):A21 March 2000
    
    
17. Kline JN, Gudmundson G, Businga TR, Jain VV. CpG Oligonucleotides  increases susceptibility to, but not severity of, Hypersensitivity Pnemonitis. Am J Respir Crit Care Med 161(3):A729 March 2000
    
    
18. O'Shaughnessy PT, Jain VV, Hearne SM, Nonnenmann MW. Generation of a respirable grain dust aerosol.  American Association of Aerosol Research August 1999
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19. Kline JN, Jain VV, Businga TR, Krieg AM.  Cpg oligonucleotides provide effective adjuvant activity in a murine model of immunotherapy for asthma. Am J Respir Crit Care Med 159(4): April 1999.
    
    
20. Kline JN, Zhoa W, Businga TR, Jain VV, Ratliff TL. Mycobacterium bovis BCG fibronectin attachment protein (FAP-B) prevents the development of airway eosinophilia and bronchial hyperreactivity in a murine model of asthma. Am J Respir Crit Care Med 159(4): April 1999.

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